Abstract: Non-ischemic central retinal vein occlusion (CRVO) can cause macular edema and impairment of  central vision. Intravitreal anti-VEGF therapy helps to reduce macular edema in CRVO, it does not work in venous stasis and elevated retinal central venous pressure (RCVP) caused by retinal venous return distrubance. Laser-induced chorioretinal venous anastomosis (L-CRVA) is helpful for transchoroidal drainage of retinal venous blood to reduce RCVP and relieve retinal venous stasis. With the development of laser, the success rate of anastomosis formation  has been improved and complications have been reduced. The combination of L-CRVA and anti-VEGF may permanently cure non-ischemic CRVO and help to reduce the burden of patients.  (Int Rev Ophthalmol, 2024, 48: 129-132)

Key words: retinal vein occlusion; , chorioretinal venous anastomosis